Controlled study of the efficacy ozone therapy in Fibromyalgia, a randomised controlled trial [abstract]

摘要

INTRODUCTION: Fibromyalgia meaning muscle and connective tissue pain it a disorder classified by the presence of chronic widespread pain and a heightened and painful response to gentle touch (tender points). Other core features of the disorder include debilitating fatigue, sleep disturbance, and joint stiffness. PURPOSE: The aim of the study is to see the efficacy of ozone in relation to other local anaesthetic and placebo for relief of pain. MATERIAL AND METHODS: The Study involved 300 patients with classical Fibromyalgia (ACR criteria) age between 45 and 70. The first group treated only with ozone 2 - 3 x per week for over 4 necks (15 mcgr/mL) The second group with local anaesthetic /Lidocain 2 % 10- 20 mL) The third group, placebo. Several clinical parameters were monitored during a demonstration in 4-6 weeks. The clinical examination included vital signs, pain using visual analog Scale, Duration of morning stiffness, night pain, NSAID consumption RESULTS AND CONCLUSION: 1.- Ozone has significant effect in Fibromyalgia in relation to the other two groups. 2.- Function index improved in both groups ozone and anaesthetic. 3.- Ozone treatment is a safe therapy compared to the local anaesthetic.