A diseased ecosystem: Tackling antibiotic resistance from a global perspective
DOI:
https://doi.org/10.7203/metode.78.2627Keywords:
eco-evo strategies, global medicine, antibiotic resistance, multi-hierarchical analysisAbstract
Man’s production of antibiotics has led to disease in microbial ecosystems on a planetary scale. The most immediate impact for man is the intractability of infections. To tackle this we must improve our understanding of this phenomenon, and develop intervention strategies employing novel conceptual, analytical and technological methods.
Downloads
References
Bapteste, E. et al., 2012. «Evolutionary Analyses of Non-genealogical Bonds Produced by Introgressive Descent». PNAS, 109(45): 18266-18272. DOI: <10.1073/pnas.1206541109>.
Baquero, F.; Coque, T. M. and F. de la Cruz, 2011. «Ecology and Evolution as Targets: the Need for Novel Eco-evo Drugs and Strategies to Fight Antibiotic Resistance». Antimicrob Agents Chemother, 55(8): 3649-3660. DOI: <10.1128/AAC.00013-11>.
Baquero, F.; Martínez, J. L. and R. Cantón, 2008. «Antibiotics and Antibiotic Resistance in Water Environments». Current Opinion in Biotechnology, 19: 260-265. DOI: <10.1016/j.copbio.2008.05.006>.
Baquero, F.; Tedim, A. P. and T. M. Coque, 2013. «Antibiotic Resistance Shaping Multilevel Population Biology of Bacteria». Frontiers in Antimicrobials, Resistance and Chemotherapy. Pre-published online: 6 March 2013. DOI: <10.3389/ fmicb.2013.00015>.
Levy, S. B., 2002. The Antibiotic Paradox. Da Capo Press. Cambridge, MA. Galán, J. C.; González-Candelas, F.; Rolain, J. M. and R. Cantón, 2013. «Antibiotics as Selectors and Accelerators of Diversity in the Mechanisms of Resistance: from the Resistome to Genetic Plasticity in the β-lactamases World». Frontiers in Antimicrobials, Resistance and Chemotherapy. Published online: 8 February 2013. DOI: <10.3389/fmicb.2013.00009>.
Linares, J. F.; Gustafsson, I.; Baquero, F. and J. L. Martínez, 2006. «Antibiotics as Intermicrobial Signaling Agents Instead of Weapons». PNAS, 103(51): 19484-19489. DOI: <10.1073/pnas.0608949103>.
Downloads
Published
How to Cite
-
Abstract601
-
PDF130
-
PDF (Català/Valencià)91
-
PDF (Español)226
Issue
Section
License
All the documents in the OJS platform are open access and property of their respective authors.
Authors publishing in the journal agree to the following terms:
- Authors keep the rights and guarantee Metode Science Studies Journal the right to be the first publication of the document, licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License that allows others to share the work with an acknowledgement of authorship and publication in the journal.
- Authors are allowed and encouraged to spread their work through electronic means using personal or institutional websites (institutional open archives, personal websites or professional and academic networks profiles) once the text has been published.